Are alpha-glucosidase inhibitors approved only for type 2 diabetes mellitus?

• A. FALSE
• B. Only for type 2 diabetes in combination with metformin
• C. Approved for type 1 diabetes as well
• D. TRUE

Answer: (D)

Alpha-glucosidase inhibitors work by delaying the breakdown of carbohydrates in the small intestine, which reduces the rise in blood glucose after meals. This mechanism targets postprandial glucose control, a key issue in type 2 diabetes management. They do not supply insulin or address autoimmune destruction of beta cells, so they aren’t approved for type 1 diabetes. In clinical practice, these agents are used in type 2 diabetes, often alongside other medications, rather than in type 1. Therefore, the statement that they are approved only for type 2 diabetes mellitus is true.